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Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
Sponsor: Johns Hopkins University
Summary
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it produces similar effects to delta-9-THC, albeit at lower potency. The present study will evaluate the dose effects of delta-8-THC, compared with delta-9-THC, on simulated driving performance, field sobriety tests, cognitive performance, and biomarkers of exposure to cannabinoids. The results will inform policy and education related to impairment due to acute delta-8-THC exposure via vaporization and oral ingestion.
Official title: The Effect of Delta-8-THC vs Delta-9-THC on Simulated Driving Performance and Measures of Impairment
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-07-01
Completion Date
2025-09-08
Last Updated
2026-07-20
Healthy Volunteers
Yes
Conditions
Interventions
Delta-9-THC
Acute self-administration of inhaled or oral ∆9-THC by healthy adult research volunteers
Delta-8-THC
Acute self-administration of inhaled or oral ∆8-THC by healthy adult research volunteers
Placebo
Consumption of a brownie or inhalation of ambient air through a cannabis vaporizer by health adult research volunteers
Locations (1)
Johns Hopkins Behavioral Pharmacology Research Unit
Baltimore, Maryland, United States