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Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad Breath
Sponsor: Semmelweis University
Summary
The ODOR trial will be a single-centric, double-blinded, parallel-group, double-armed pilot randomized controlled trial with a non-inferiority design. The efficacy of hyperpure chlorine dioxide will be compared to chlorhexidine mouthwash. The short-term effect of the mouthwashes will be investigated in a 3-hour-long period. The primary endpoint will be the changes in the organoleptic testing scores.
Official title: Hyperpure Chlorine Dioxide Versus Chlorhexidine in Intra-oral Halitosis (ODOR Trial)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-04-18
Completion Date
2025-12-18
Last Updated
2025-08-05
Healthy Volunteers
No
Conditions
Interventions
Chlorine dioxide mouthwash
This one rinsing will last 2x15 seconds(2x12,5ml).
Chlorhexidine mouthwash
This one rinsing will last 2x15 seconds(2x12,5ml).
Locations (1)
Semmelweis University
Budapest, Budapest, Hungary