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Short-term And Longer-term Cognitive Impact Of Neurochecks
Sponsor: University of California, San Diego
Summary
The proposed research plan seeks to understand the impact of sleep disruption in the Neurological Intensive Care Unit (ICU) on older patients with acute brain injury (ABI). In current practice, the neurocritical care community performs frequent serial neurological examinations ("neurochecks") in an effort to monitor patients for neurological deterioration following brain injury. Many neurocritical patients are older and/or cognitively fragile, and delirium is common. Although ICU delirium is multifaceted, frequent neurochecks may represent a modifiable risk factor if the investigators can better understand the risks and benefits of various neurocheck frequencies. This project will randomize patients with acute spontaneous intracerebral hemorrhage (ICH) to either hourly (Q1) or every-other-hour (Q2) neurochecks and evaluate the impact of neurocheck frequency on delirium. Second, longer-term cognitive outcomes will be investigated in patients with ICH randomized to Q1 versus Q2 neurochecks with the goal of identifying whether hourly neurochecks increase the risk for dementia.
Official title: Short-term And Longer-term Cognitive Impact Of Hourly Neurochecks In Acute Brain Injury
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2024-07-08
Completion Date
2029-10-31
Last Updated
2025-09-10
Healthy Volunteers
No
Conditions
Interventions
Frequency of neurochecks
the frequency with which a patient is awakened to perform serial examinations
Locations (1)
UC San Diego Health
San Diego, California, United States