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RECRUITING
NCT06219889
NA

Short-term And Longer-term Cognitive Impact Of Neurochecks

Sponsor: University of California, San Diego

View on ClinicalTrials.gov

Summary

The proposed research plan seeks to understand the impact of sleep disruption in the Neurological Intensive Care Unit (ICU) on older patients with acute brain injury (ABI). In current practice, the neurocritical care community performs frequent serial neurological examinations ("neurochecks") in an effort to monitor patients for neurological deterioration following brain injury. Many neurocritical patients are older and/or cognitively fragile, and delirium is common. Although ICU delirium is multifaceted, frequent neurochecks may represent a modifiable risk factor if the investigators can better understand the risks and benefits of various neurocheck frequencies. This project will randomize patients with acute spontaneous intracerebral hemorrhage (ICH) to either hourly (Q1) or every-other-hour (Q2) neurochecks and evaluate the impact of neurocheck frequency on delirium. Second, longer-term cognitive outcomes will be investigated in patients with ICH randomized to Q1 versus Q2 neurochecks with the goal of identifying whether hourly neurochecks increase the risk for dementia.

Official title: Short-term And Longer-term Cognitive Impact Of Hourly Neurochecks In Acute Brain Injury

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2024-07-08

Completion Date

2029-10-31

Last Updated

2025-09-10

Healthy Volunteers

No

Interventions

BEHAVIORAL

Frequency of neurochecks

the frequency with which a patient is awakened to perform serial examinations

Locations (1)

UC San Diego Health

San Diego, California, United States