Clinical Research Directory

Inclusion Criteria: 1. Natural menopause, last menstrual period more than one year ago. 2. Abnormal lipid profile parameters The criteria set for this research are: * LDL\>130 mg/Dl or * TG\>150 mg/Dl or * Total cholesterol\>200 mg/Dl or * HDL-C less than 50 mg/Dl. (Latest blood results not more than 6 months) 3. Willing to participate in the project Exclusion Criteria: 1. Have ever received lipid-lowering medication or hormone replacement therapy or SERMs. During the past 6 weeks 2. have had surgery on the ovaries or uterus before 3. have a history of cancer within a 5-year period 4. have diabetes or uncontrolled high blood pressure, including HbA1c \>9, Systolic blood pressure \>180 or Diastolic blood pressure \>110 5. Endocrine system disease such as thyroid 6. Ever had an organ transplant 7. Regularly use drugs, marijuana, or drink alcohol. 8. has a psychiatric disorder 9. have other serious medical conditions that require close monitoring 10. Inconvenient to follow up until the end of the research.