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Getting Under the Skin of the Menopausal Hot Flush
Sponsor: Liverpool John Moores University
Summary
The aim of this research is to 1) test how the skin blood vessels and sweat glands function in women who experience hot flushes by using skin microdialysis to deliver small amounts of substances to the skin that cause increased skin blood flow and sweating, and 2) examine the structure of the skin blood vessels and sweat glands in the skin of women who experience hot flushes by taking a very small skin biopsy. Any changes in the function or structure of the skin blood vessels or sweat glands in women with hot flushes would increase our understanding of what causes hot flushes and help to design effective treatments.
Official title: The Menopausal Hot Flush: Cutaneous Vascular and Sudomotor Function and Structure in Symptomatic Women
Key Details
Gender
FEMALE
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
36
Start Date
2023-01-01
Completion Date
2025-12-31
Last Updated
2025-03-18
Healthy Volunteers
Yes
Conditions
Locations (1)
Liverpool John Moores University
Liverpool, Merseyside, United Kingdom