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ENROLLING BY INVITATION
NCT06223074
PHASE2

Improving the Treatment of Acute Relapses in Multiple Sclerosis Through Intranasal Methylprednisolone Administration

Sponsor: Universidad Nacional Autonoma de Mexico

View on ClinicalTrials.gov

Summary

This Clinical Trial evaluates the nasal administration of Methylprednisolone as a treatment strategy for Acute Relapses in Multiple Sclerosis

Official title: Towards the Improvement of the Treatment of Acute Relapses in Multiple Sclerosis: A Randomized Double-blind, Non-inferiority Controlled Trial Comparing Intranasal Versus Intravenous Methylprednisolone

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2023-01-09

Completion Date

2026-07-05

Last Updated

2025-04-03

Healthy Volunteers

No

Interventions

OTHER

IV Methylprednisolone administration

Group 1 will receive 1g methylprednisolone IV for 3 or 5 days, according to the severity of the relapse

DRUG

Nasal Methylprednisolone (MT)

Group 2 will receive the dose intranasal equivalent to 1g of methylprednisolone for 3 or 5 days according to the severity of the relapse

Locations (1)

Instituto Nacional de Neurología y Neurocirugía

Mexico City, Mexico