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NOT YET RECRUITING
NCT06227286
NA

Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER)

Sponsor: Sun Yat-sen University

View on ClinicalTrials.gov

Summary

The goal of this multicenter, randomized, double-blind controlled study is to learn about the individuals after transcatheter edge-to-edge mitral valve repair (TEER). The main questions it aims to answer are: (1) can enhanced external counterpulsation (EECP) reduce the prevalence of afterload mismatch after TEER? (2) can EECP prevent the major adverse cardiac events after TEER? Participants will be randomly assigned into EECP or Sham-EECP intervention after TEER. Researchers will compare the EECP and Sham-EECP to see if it helps reduce the prevalence of afterload mismatch after TEER.

Official title: Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER): A Multicenter, Randomized, Double-blind Controlled Study

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

176

Start Date

2024-03-01

Completion Date

2028-12-31

Last Updated

2024-02-05

Healthy Volunteers

No

Interventions

DEVICE

EECP

EECP: 30-45 minutes/day, 5 days/week, 7 weeks, initiates with 0.030MPa.

DEVICE

Sham-EECP

EECP: 30-45 minutes/day, 5 days/week, 7 weeks, constant to 75 mmHg.

Locations (6)

First Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, China

Second Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Third Affiliated Hospital, Sun Yat-Sun University

Guangzhou, Guangdong, China

Jieyang People's Hospital

Jieyang, Guangdong, China

Second Affiliated Hospital of Shantou University Medical College

Shantou, Guangdong, China

Zhongshan People's Hospital

Zhongshan, Guangdong, China