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Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER)
Sponsor: Sun Yat-sen University
Summary
The goal of this multicenter, randomized, double-blind controlled study is to learn about the individuals after transcatheter edge-to-edge mitral valve repair (TEER). The main questions it aims to answer are: (1) can enhanced external counterpulsation (EECP) reduce the prevalence of afterload mismatch after TEER? (2) can EECP prevent the major adverse cardiac events after TEER? Participants will be randomly assigned into EECP or Sham-EECP intervention after TEER. Researchers will compare the EECP and Sham-EECP to see if it helps reduce the prevalence of afterload mismatch after TEER.
Official title: Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER): A Multicenter, Randomized, Double-blind Controlled Study
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
176
Start Date
2024-03-01
Completion Date
2028-12-31
Last Updated
2024-02-05
Healthy Volunteers
No
Conditions
Interventions
EECP
EECP: 30-45 minutes/day, 5 days/week, 7 weeks, initiates with 0.030MPa.
Sham-EECP
EECP: 30-45 minutes/day, 5 days/week, 7 weeks, constant to 75 mmHg.
Locations (6)
First Affiliated Hospital, Sun Yat-Sen University
Guangzhou, Guangdong, China
Second Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
Third Affiliated Hospital, Sun Yat-Sun University
Guangzhou, Guangdong, China
Jieyang People's Hospital
Jieyang, Guangdong, China
Second Affiliated Hospital of Shantou University Medical College
Shantou, Guangdong, China
Zhongshan People's Hospital
Zhongshan, Guangdong, China