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ENROLLING BY INVITATION
NCT06230887
NA

Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

Moral Injury Syndrome (MIS) affects up to 35-60% of Veterans managing combat-related PTSD; it results from experiences that challenge deeply held values or spiritual beliefs. Symptoms of MIS may include hopelessness, helplessness, loss of spiritual beliefs, difficulty with forgiveness, loss of meaning or purpose, reduced trust in self or others, or intractable guilt, shame or anger. Veterans managing MIS have difficulty responding to mental health treatment, and are at increased risk for suicide ideation or attempts. To date evidence-based interventions for MIS are not widely available in VA. This study will implement an evidence-based intervention for MIS in four VA facilities, collect data on the effectiveness of the intervention, and develop an implementation toolkit. This data will inform national dissemination in collaboration with the Office of Mental Health and Suicide Prevention and the National Chaplain Service.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2024-07-30

Completion Date

2028-07-31

Last Updated

2025-07-04

Healthy Volunteers

No

Interventions

BEHAVIORAL

Building Spiritual Strength

Spiritually Integrated group intervention for moral injury

BEHAVIORAL

Present Centered Group Therapy

Active control, manualized evidence-based coping skills intervention for PTSD

Locations (5)

Central Arkansas Veterans Healthcare System , Little Rock, AR

Little Rock, Arkansas, United States

Atlanta VA Medical and Rehab Center, Decatur, GA

Decatur, Georgia, United States

Maine VA Medical Center, Augusta, ME

Augusta, Maine, United States

Minneapolis VA Health Care System, Minneapolis, MN

Minneapolis, Minnesota, United States

Michael E. DeBakey VA Medical Center, Houston, TX

Houston, Texas, United States