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A Pilot Study of Efficacy and Safety of SIM05 in Adults With Atopic Eczema
Sponsor: Chinese University of Hong Kong
Summary
Atopic eczema causes significant disease burdens worldwide. Some studies reported gastrointestinal symptoms in eczema patients which could be related to gut microbiota change. A unique gastrointestinal microflora pattern has also been observed in atopic dermatitis patients when compared with healthy controls. To date, no adult formula is specific for alleviating atopic eczema-related symptoms (especially through change of gut microbiota) for adults. The investigators hypothesize that the gut microbiota of adults with atopic eczema can be modulated to decrease the severity of atopic eczema-related symptoms. A pilot study is proposed to assess the effect and safety of SIM05 on atopic eczema severity and gut microbiome of adults with atopic eczema.
Official title: A Pilot Study of Efficacy and Safety of a Microbiome Immunity Formula (SIM05) in Adults With Atopic Eczema
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-10-10
Completion Date
2025-12-28
Last Updated
2025-03-28
Healthy Volunteers
No
Conditions
Interventions
SIM05
SIM05 contains a blend of food-grade Bifidobacterium and Lactobacillus strains plus prebiotics
Locations (1)
Prince of Wales Hospital
Hong Kong, Hong Kong