Clinical Research Directory

Inclusion Criteria: * The presence of purulent-inflammatory processes of the skin and soft tissues due to the neuropathic form of diabetic foot syndrome (Main diagnosis: Diabetes mellitus type I or II, clinical metabolic compensation/subcompensation, class I - II according to the Wagner classification) or chronic venous insufficiency (Main diagnosis: Varicose veins dilatation of the veins of the lower extremities, class C6 according to the CEAP classification), phase I-II of the wound process * The size of the ulcerative defect is from 1 cm² to 20 cm² * Secondary type of wound healing * Absence of exposed bones and tendons in the wound * Absence of severe concomitant diseases in the stage of decompensation, oncological diseases, as well as diseases requiring steroid therapy * Availability of written informed consent from the patient to participate in the study * The patient's ability to follow the instructions of the research physician and comply with the study regimen Exclusion Criteria: * Individual intolerance or hypersensitivity reactions to the components of the drug Foscelantan * Neuroischemic form of diabetic foot syndrome * The presence of serious concomitant pathology (severe form of renal and hepatic failure, systemic connective tissue diseases, severe cardiovascular insufficiency), history and current mental illness * The need to constantly take drugs from the list of prohibited therapies * Participation of the patient in another clinical trial within 3 months before the current clinical trial * Acute bleeding * Level of peripheral blood leukocytes less than 1.5 × 109 per l, platelets less than 75.0 × 109 per l. * Hemoglobin less than 80g per l. * Positive tests for syphilis, human immunodeficiency virus (HIV), hepatitis B, or hepatitis C * Severe liver dysfunction - AST or ALT levels exceed the upper limit of normal by 5 times or more, bilirubin ≥ 2.0 mg/dL (34.2 µmol/L). * Severe renal dysfunction - creatinine 2 times higher than reference values * Diabetes mellitus in a state of clinical and metabolic decompensation * Pregnant and breastfeeding women * At one\'s own request without explaining the reasons for the action. * At the request of the research physician, if the research subject violates the protocol requirements for diet, consumption of alcoholic beverages, and medications without the prescription of the research physician. * For reasons independent of the study subject and the research physician, when a study subject develops drug intolerance and other life-threatening or requiring emergency pharmacotherapy adverse reactions to the administration of the study drug. * The need to prescribe drugs from the list of prohibited treatments.