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Cognitive Enhancement Through Model-based and Individualized Neurostimulation
Sponsor: Washington University School of Medicine
Summary
The goal of this clinical trial is to learn about the effects of transcranial electric stimulation on attentional control and brain dynamics in healthy adults. The main questions are: Does stimulation affect how subjects exert attentional control? Do mathematical models predict brain activity changes in response to stimulation? Participants will have electroencephalography (EEG) brain data recorded while: They sit relaxed They receive stimulation, while relaxed They receive stimulation while completing computerized tasks to measure cognitive abilities ("cognitive tasks") They receive sham (ineffective) stimulation during cognitive tasks
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2024-02-13
Completion Date
2025-12-31
Last Updated
2026-05-07
Healthy Volunteers
Yes
Interventions
Transcranial electrical stimulation (tES) including SHAM
Transcranial electrical stimulation, known as tES, refers to a family of devices that utilize low-cost technologies and involve low-intensity currents which are safe for humans, and carry minimal risk of side effects or adverse events. Conventional approaches, which utilize fixed direct currents (tDCS) or alternating currents at a fixed oscillatory frequency (tACS), have been widely used as both a basic research tool and as a clinical intervention. In the current project, we use a custom-built device that enables near real-time current modulation triggered digitally, via software control, to allow for stimulation protocols guided by whole-brain individualized neural modeling.
Locations (1)
Washington University
St Louis, Missouri, United States