Clinical Research Directory

Main Inclusion Criteria: * I1. From 18 to 70 years (including ranges); * I2. BMI of ≥18.5 and ≤35 kg/m²; * I3. Moderately hypercholesterolemic subject without any clinical symptoms of hypercholesterolemia (xanthoma, recurrent chest and/or leg pain…) and not requiring immediate pharmacological lipid-lowering treatment; * I4. Weight stable within ± 5% in the last three months before V0; * I5. SCORE2 - SCORE2-OP (Older Persons) Cardiovascular Risk Chart Main Exclusion Criteria: * E1. Suffering from a metabolic disorder such as diabetes, uncontrolled thyroidal dysfunction or other metabolic disorder needing a dose adjustment in drug intervention according to the professional recommendations; * E2. Suffering from an uncontrolled arterial hypertension; * E3. With a history of ischemic cardiovascular event; * E4. Having undergone recent surgical procedure in the past 6 months before V0 or planned in the 5 months to come; * E5. History of bariatric surgery; * E6. Suffering from a severe chronic disease; * E7. For women: ongoing pregnancy (as evidenced by a positive test for β-Human Chorionic Gonadotropin, i.e. \> 5 mUI/mL, realized at V0) or breastfeeding or finished since less than 6 months before V0 or intending to become pregnant within 5 months ahead; * E8. Under cholesterol and/or lipid-lowering treatment or stopped less than 3 months before the inclusion visit V0; * E9. Under medication which could affect blood lipid parameters or stopped less than 3 months before the inclusion visit V0 (antihypertensive stable long-term treatment tolerated); * E10. Consuming more than 3 standard drinks daily of alcoholic beverage for men or 2 standard drinks daily for women