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Comparison of Apixaban Versus Enoxaparin
Sponsor: Abramson Cancer Center at Penn Medicine
Summary
The goal of this randomized trial is to compare bladder cancer patient experiences taking prophylactic anticoagulation at home after surgery to remove their bladder. The main questions it aims to answer are: * Are patients equally adherent to apixaban as they are enoxaparin? Why or why not? * Do patients prefer apixaban or enoxaparin? * What is the typical patient cost to take apixaban vs enoxaparin after surgery? Participants will be randomized to receive a prescription for either enoxaparin or apixaban which they will then fill themselves and self-administer at home until post-operative day 30. They will receive phone calls from study coordinators at days 30 and 90 to complete questionaries over the phone to assess trial outcomes.
Official title: Comparison of Apixaban Versus Enoxaparin as Venous Thromboembolism Prophylaxis After Radical Cystectomy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2023-11-24
Completion Date
2026-06
Last Updated
2026-01-28
Healthy Volunteers
No
Conditions
Interventions
apixaban
Participants will be randomized to receive a prescription for prophylactic apixaban
enoxaparin
Participants will be randomized to receive a prescription for prophylactic enoxaparin
Locations (1)
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States