Clinical Research Directory

Inclusion Criteria: 1. Patients who voluntarily take the test and sign the informed consent form; 2. Patients aged 18-65 years old with no history of allergies; 3. Patients able to communicate well with the investigator and follow the requirements of the entire trial. Exclusion Criteria: 1. Patients who refuse to sign the informed consent form to participate in the trial; 2. Patients who are not in the age range of 18 to 65 years; 3. Patients with diseases unsuitbale for the trial: history of allergies, severe cardiopulmonary disease, coagulation dysfunction, Alzheimer's disease, cerebral atrophy, acute phase or sequelae of cerebrovascular disease, cognitive impairment; 4. Patients in the acute phase of local or systemic bacterial infections; 5. Patients who cannot cooperate with the operation and evaluate the effect; 6. Other conditions that are considered inappropriate by the investigator to participate in the study.