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NOT YET RECRUITING
NCT06250413
NA

Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics

Sponsor: Otto Helve

View on ClinicalTrials.gov

Summary

In this clinical trial, our aim is to assess the effect of auto-FMT (Fecal microbiome transplantation) on the intestinal microbiota, after a course of antibiotics. 30 healthy adults are recruited. All are given a five day course of amoxicillin-clavulanate. The subjects are double blinded and randomized to two groups. Group A is given autologous FMT (auto-FMT) on day 7 (two days after the end of the course of antibiotics) and Group B is given auto-FMT on day 28 (23 days after the end of the course of antibiotics).

Official title: Lyophilized Capsulated Autological Fecal Microbial Transplant to Restore Gut Microbiome After Treatment With Antibiotics

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-02

Completion Date

2027-12

Last Updated

2024-02-14

Healthy Volunteers

Yes

Interventions

OTHER

FMT

Capsulated oral auto fecal microbiota transplant

OTHER

Placebo

Capsulated hot chocolate powder

DRUG

Amox Clav

5 day course of Amoxicillin Clavulanic acid given to all participants

Locations (1)

Helsinki University Hospital

Helsinki, Uusimaa, Finland