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Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics
Sponsor: Otto Helve
Summary
In this clinical trial, our aim is to assess the effect of auto-FMT (Fecal microbiome transplantation) on the intestinal microbiota, after a course of antibiotics. 30 healthy adults are recruited. All are given a five day course of amoxicillin-clavulanate. The subjects are double blinded and randomized to two groups. Group A is given autologous FMT (auto-FMT) on day 7 (two days after the end of the course of antibiotics) and Group B is given auto-FMT on day 28 (23 days after the end of the course of antibiotics).
Official title: Lyophilized Capsulated Autological Fecal Microbial Transplant to Restore Gut Microbiome After Treatment With Antibiotics
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-02
Completion Date
2027-12
Last Updated
2024-02-14
Healthy Volunteers
Yes
Interventions
FMT
Capsulated oral auto fecal microbiota transplant
Placebo
Capsulated hot chocolate powder
Amox Clav
5 day course of Amoxicillin Clavulanic acid given to all participants
Locations (1)
Helsinki University Hospital
Helsinki, Uusimaa, Finland