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Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
Sponsor: United States Naval Medical Center, Portsmouth
Summary
Perform a comparison of effective pain relief duration between liposomal bupivacaine and dexmedetomidine when added to bupivacaine in a block for mastectomy for cancer surgery. The erector spinae plane block is a well-established block that is utilized for post operative pain control for procedures performed on the soft tissue of the chest and chest wall as well as intrathoracic procedures. The goal is comparison of the effective duration of both study groups to determine if there is a significant difference in time and amount of post operative opioids required which admitted to hospital.
Official title: Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in an Erector Spinae Plane Block for Mastectomies in Cancer Patients: a Randomized Control Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-10-15
Completion Date
2025-10
Last Updated
2024-11-19
Healthy Volunteers
Yes
Conditions
Interventions
Dexmedetomidine
block duration extension additive
Liposomal bupivacaine
Control arm, comparison for block duration with dexmedetomidine
Locations (1)
Naval Medical Center Portsmouth
Portsmouth, Virginia, United States