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RECRUITING
NCT06252922

Diet-Induced Changes in GEnetic Material

Sponsor: Pennington Biomedical Research Center

View on ClinicalTrials.gov

Summary

This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in sperm associated with obesity and cardiometabolic dysfunction.

Official title: A Pilot Study to Examine Metabolic Flexibility as a Mechanism for Diet- Induced Epigenetic Alterations in Male Gametes

Key Details

Gender

MALE

Age Range

20 Years - 35 Years

Study Type

OBSERVATIONAL

Enrollment

10

Start Date

2023-11-11

Completion Date

2026-12-30

Last Updated

2025-05-31

Healthy Volunteers

Yes

Locations (1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States