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The Role of Cxcr4Hi neutrOPhils in InflueNza
Sponsor: University Hospital, Bordeaux
Summary
Influenza is still responsible for more than 650,000 deaths per year worldwide and no major improvements in patients' care has been made despite 50 years of research. Especially, there is no therapeutic strategy targeting the dysregulated host response. CXCR4-expressing neutrophils seem to be involved in the rupture of host resistance. The aim of this study is thus to compare the percentage of blood CXCR4-expressing neutrophils between influenza survivors and non-survivors.
Official title: The Role of CXCR4-expressing Neutrophils in Influenza-related Acute Respiratory Distress Syndrome
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
90
Start Date
2024-12
Completion Date
2026-12
Last Updated
2024-12-27
Healthy Volunteers
No
Interventions
Additional tubes and LBA
4 Additional tubes taken when blood is drawn during treatment : EDTA tubes and 2 citrate tubes and bronchoalveolar fluid sample (LBA)
Locations (2)
Hopital Pellegrin
Bordeaux, France
Hopital Haut-Lévêque
Pessac, France