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Fecal Transplantation in Patients Colonic Diverticulitis
Sponsor: Odense University Hospital
Summary
The goal of this clinical trial is to investigate the safety and effect of fecal microbiome transplantation (FMT) in patients with a former episode of acute colonic diverticulitis. The main question\[s\] it aims to answer are: * Is FMT in patients with a former episode of acute colonic diverticulitis a safe procedure without severe adverse events * What is the impact of FMT on patient-reported outcomes and re-admission rate Participants will be asked to: * to ingest either 25-30 capsules with FMT or placebo capsules * Fill-in GI-QLI questionnaire prior to treatment/placebo and 3 months post baseline * Fill-in eating habit questionnaire * deliver blood-and stool samples prior to treatment/placebo and 3 months post baseline * In both the treatment and placebo group 5 patients will be offered sigmoideoscopy for mucosal biopsies if it is more than 2 items\]. If there is a comparison group: Researchers will compare \[insert groups\] to see if \[insert effects\]
Official title: Fecal Transplantation in Patients With Colonic Diverticulitis: a Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-04-01
Completion Date
2024-12-31
Last Updated
2024-04-05
Healthy Volunteers
Yes
Conditions
Interventions
Fecal Microbiome
Fecal microbiome transplantation from a healthy donor.
Placebo
Place capsules
Locations (1)
Odense University Hospital
Odense, Funen, Denmark