Clinical Research Directory

Inclusion Criteria: * 6-30 years old * Have the diagnosis of autism spectrum disorder * ADOS-2 score is higher than the ASD cut-offs * Comorbid with intelligent disorder, IQ/DQ \< 70 * Primary environmental language is Chinese * Participant's parents or other legal guardians give informed consent Exclusion Criteria: * Genetic Disorders, such as (e.g., Down syndrome, Fragile X syndrome, Rett syndorme), Current or history of severe ADHD, tourette syndrome, psychotic disorders (e.g., schizophrenia, schizoaffective disorder, bipolar disorder) * Severe self-injury or suicidal behavior exhibited within the past year * Significant visual, auditory, deafness or motor disability that prevent them from following study procedures * Current or history diagnosis of epilepsy * Known severe physical diseases, particularly those affecting the brain * Metal implantation contradicted by MRI or TMS, such as artificial cardiac pacemakers, stents, cochlear implants * Respiratory or circulatory conditions increasing sedation risk, such as Apnea syndrome, severe snoring, or other relevant diseases * All legal guardians are illiterate, unable to read informed documents or complete questionnaires independently * Received transcranial magnetic stimulation (TMS), transcranial current stimulation (tCS), focused ultrasound (FUS), or other neuromodulation treatment in the last 3 months * Current participation in other clinical trials