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RECRUITING
NCT06256575
NA

Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

Sponsor: Primus Pharmaceuticals

View on ClinicalTrials.gov

Summary

This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.

Official title: Treatment of Digital Ulcers in Systemic Sclerosis With Diosmin: A Randomized, Double-blind, Placebo-controlled Multi-centre Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

45

Start Date

2025-05-02

Completion Date

2027-08-15

Last Updated

2025-12-04

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

Diosmin

A medical food of diosmin and alka4-complex

OTHER

Placebo

Corn starch one (1) capsule twice daily

Locations (5)

University of Calgary

Calgary, Alberta, Canada

Dalhousie University

Halifax, Nova Scotia, Canada

Saint Joseph Health Care Centre

London, Ontario, Canada

The Ottawa Hospital

Ottawa, Ontario, Canada

Mount Sinai Health System

Toronto, Ontario, Canada