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Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
Sponsor: Primus Pharmaceuticals
Summary
This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.
Official title: Treatment of Digital Ulcers in Systemic Sclerosis With Diosmin: A Randomized, Double-blind, Placebo-controlled Multi-centre Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2025-05-02
Completion Date
2027-08-15
Last Updated
2025-12-04
Healthy Volunteers
No
Conditions
Interventions
Diosmin
A medical food of diosmin and alka4-complex
Placebo
Corn starch one (1) capsule twice daily
Locations (5)
University of Calgary
Calgary, Alberta, Canada
Dalhousie University
Halifax, Nova Scotia, Canada
Saint Joseph Health Care Centre
London, Ontario, Canada
The Ottawa Hospital
Ottawa, Ontario, Canada
Mount Sinai Health System
Toronto, Ontario, Canada