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A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
Sponsor: Ohio State University Comprehensive Cancer Center
Summary
This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers. ECs may reduce cigarette craving and withdrawal symptoms, increase motivation and confidence to stop cigarette smoking, and decrease cigarette smoking and dependence. By comparing participants' preferred flavor ECs (PEC) to tobacco flavor ECs (TEC) to NRT, researchers hope to determine the effect of EC flavors on appeal and use and learn how ECs affect smoking behaviors and health.
Official title: A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-Cigarettes on Smoking Behavior
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1500
Start Date
2024-04-10
Completion Date
2028-04-12
Last Updated
2026-04-06
Healthy Volunteers
Yes
Conditions
Interventions
Nicotine Replacement
Given nicotine patches and nicotine lozenges
Questionnaire Administration
Ancillary studies
Vaping
Given Preferred Flavor e-liquid
Vaping
Given Tobacco flavored e-liquid
Locations (1)
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States