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Biomechanical and Morphological Characterization of PTTD
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
Posterior tibial tendon dysfunction (PTTD) is a progressive condition of the tendon of the tibialis posterior muscle with symptoms of tendinopathy or even rupture. Functionally, it is associated with the inability to lock the mid foot and thus manifests itself as a main contributor to adult acquired flatfoot deformity. Concerning treatment, clinical decision making is currently based on a classification integrating various parameters as pain, flexibility of the foot joints, the condition of the posterior tibial tendon assessed through ultrasound imaging and radiographic assessment of arthritic changes. Surprisingly, this classification does not consider any morphologic characteristics (the shape of a bone or joint) or functional, biomechanical characteristics of the foot and ankle, i.e. based on kinematics (e.g. range of motion) and/or kinetics (center of pressure, angular velocity, moment, power absorption and power generation of a joint). Detailed biomechanical characteristics of the foot and ankle can be reliably collected by instrumented gait analysis wherein a 3D camera system is combined with a force plate and plantar pressure platform. Kinematic studies in the field of PTTD typically considered the foot as a structure consisting of three segments: hind foot, forefoot and hallux. Consequently, the mid foot segment (the Chopart and Lisfranc joints) has been neglected, although it is this segment that is particularly affected in PTTD patients. The aim of this research is to overcome the limitations of the current classification system and treatment of PTTD patients, by complementing the current standard-of-care clinical assessment with better insight in the pathologic changes that occur in PTTD patients.
Official title: Biomechanical and Morphological Characterization of the Foot in Patients With Posterior Tibial Tendon Dysfunction.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-08-22
Completion Date
2028-08-01
Last Updated
2025-04-15
Healthy Volunteers
Yes
Conditions
Interventions
Radiography
X-rays of the ankle; anterior-posterior, lateral, Mortise view and hindfoot alignment view. Standard weight bearing x-rays of the foot; anterior-posterior, lateral and oblique view.
Ultrasound
Ultrasound of the posterior tibial tendon to see if there is an irritation, elongation or rupture.
MRI
MRI when ultrasound is not conclusive to identify an irritation, elongation or rupture of the posterior tibial tendon.
CT-scan
CT-scan to identify arthritis of the tibial-talar, subtalar and/or Chopart joints.
Gait analysis
This lab is equipped with a 10-meter walkway surrounded by a passive optoelectronic motion analysis system consisting of 10 cameras to track the motion of markers. In the middle of the walkway, a force plate is integrated, with a pressure plate placed on top.
Locations (1)
UZ Leuven
Leuven, Vlaams-Brabant, Belgium