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Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.
Sponsor: ART Fertility Clinics LLC
Summary
One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes.
Official title: Antioxidants-enriched Single-step vs Global Total Single-step Embryo Culture Media: Effect on Blastocyst Euploidy Rates.
Key Details
Gender
All
Age Range
18 Years - 43 Years
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2024-02-01
Completion Date
2025-12-31
Last Updated
2025-02-21
Healthy Volunteers
Yes
Conditions
Interventions
antioxidants-enriched culture medium (Gx)
Blastocyst will be in continuous culture conditions (parallel antioxidants-enriched culture medium (Gx) and Global total one step media (GT) without refreshment on day 3. A refreshment of the media will be done on D5 in both groups.
Locations (1)
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates