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Improving Safety and Accuracy of Stereotactic Brain Biopsies in Primary Central Nervous System Lymphoma.
Sponsor: IRCCS San Raffaele
Summary
Primary central nervous system lymphoma (PCNSL) is an aggressive extranodal non- Hodgkin lymphoma exclusively localized into the nervous system. The aim of this study is to evaluate the MRI imaging characteristics of the peritumoral area (PTA) and to correlate this information to pathological findings.
Official title: Improving Safety and Accuracy of Stereotactic Brain Biopsies in Primary Central Nervous System Lymphoma (PCNSL): Integration of Advanced MRI Patterns and Fluorescein Sodium Fluorescence
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
15
Start Date
2021-10-01
Completion Date
2029-12-31
Last Updated
2025-06-11
Healthy Volunteers
No
Conditions
Interventions
MRI imaging
To characterize the peritumoral area in PCNLs through the use of advanced MRI sequences.
Cerebral biopsy
To evaluate the predictive value of sodium fluorescence to confirm ex-vivo the diagnostic tumor tissue prior to histopathological examination.
Locations (1)
IRCCS San Raffaele Scientific Institute
Milan, Milan, Italy