Clinical Research Directory

Inclusion Criteria: 1. Women aged 18-52 years old. 2. Regular menstruation with a cycle of 28-35 days. 3. No sexual intercourse 1 week before the operation. 4. No systemic or local use of antibiotics and probiotics for 6 months prior to surgery. 5. No history of acute or chronic pelvic inflammatory disease. 6. Subjects fully understand the significance of the study and sign the informed consent form. Exclusion Criteria: 1. In pregnancy. 2. Intraoperative conditions or pathological examination suggest a malignant or junctional disease. 3. Severe anatomical abnormalities of the pelvis. 4. Pelvic contamination with large amounts of blood during laparoscopic operation. 5. History of gene therapy, blood transfusion, stem cell therapy, or bone marrow transplantation 6. Psychiatric, personality disorders, or abuse of psychoactive substances. 7. Immunodeficiencies, allergies, or autoimmune diseases. 8. Contraindications to endotracheal intubation anesthesia. 9. Absolute or relative contraindications to laparoscopic or hysteroscopic surgery.