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ENROLLING BY INVITATION
NCT06267222
NA

Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia

Sponsor: Laura Alice Santos de Oliveira

View on ClinicalTrials.gov

Summary

The main goal of this pragmatic clinical trial is to investigate the effects of trans-spinal tDCS in individuals with spinocerebellar ataxia (SCA) over some parameters of gait and postural control in real-world conditions, reflecting daily clinical practice. The main questions it aims to answer are: * If an extended number of tDCS sessions, beyond the typical 5 to 10 sessions described in scientific literature, applied concomitantly with exercises with progressive challenges, to yield positive outcomes over some parameters of gait and postural control in individuals with SCA and if there is retention of possible benefits one month later the end of this protocol. * If there is specific characteristics (including balance, gait, mobility, severity of ataxia, DNA test characteristics and non-ataxic signs) in individuals with SCA that can predict their improvement in postural control and gait following the 20 tDCS sessions. * Participants will receive 20 tDCS sessions concomitantly with exercises for gait and postural control with progressive challenges. * Postural control and gait of the participants will be assessed in two big sessions before (#assessment 1) and after the 20 sessions (#assessment 5) and 3 small sessions after every 5 sessions (#assessments 2, 3 and 4). Also, as a follow-up, they will be assessed a month after the end of the intervention (#assessment 6).

Official title: Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia: a Pragmatic Study

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

45

Start Date

2024-05-09

Completion Date

2024-07-31

Last Updated

2024-06-10

Healthy Volunteers

No

Interventions

DEVICE

TRANSCRANIAL DIRECT CURRENT STIMULATION + exercises

Participants with SCA will receive trans-spinal tDCS and exercises. There will be no control group or sham stimulation. All participants will receive real tDCS stimulation

Locations (1)

Instituto de Neurologia Deolindo Couto

Rio de Janeiro, Rio de Janeiro, Brazil