Clinical Research Directory

Inclusion Criteria: * age ≥18 years; * First-time recipient of unilateral total HA or hemiarthroplasty; * Postoperative wound healing delay risk, defined as epithelialization \<50% at 2 weeks postoperatively (quantified using a standardized manual planar measurement method: on day 14 postoperatively, a (quantified using a standardized manual planar measurement method: on day 14 postoperatively, a standardized transparent grid membrane with 1mm² graduations is placed vertically over the wound, and the wound perimeter and epithelialization boundary are marked with a surgical marker. boundary are marked with a surgical marker pen; the epithelialized area is defined as pink, non-exudative tissue completely covering the dermis); Normal cognitive and communication abilities; * Ability to comply with relevant nursing measures; * Voluntary participation in this trial * Voluntary participation in this trial and signed informed consent form. Exclusion Criteria: * Active infection at the surgical site prior to initial hip surgery; Deep surgical site infection (SSI) or periprosthetic joint infection (PJI) diagnosed or strongly suspected at screening. diagnosed or strongly suspected at screening (based on clinical symptoms, imaging, or aspiration results according to the MSIS/EBJIS criteria); * Complete wound dehiscence (\>2 cm) or exposure of the prosthesis/bone cement, requiring emergency revision surgery; * Severe vascular insufficiency (ABI \<0.5 cm); * Severe acute and chronic chronic disease (ABI \<0.5 cm) insufficiency (ABI \<0.6, severe limb ischemia); * Uncontrolled systemic conditions severely impairing healing potential: severe malnutrition or obesity (BMI≥ 40 kg/m² or≤ 16 kg/m² or serum albumin \<2.5 g/dL); Uncontrolled diabetes (HbA1c \>9% in the past 3 months); severe heart failure (NYHA IV); severe liver dysfunction (Child-Pugh C); severe renal failure requiring dialysis; active malignant tumors; immunosuppressive therapy (high-dose corticosteroids \>10 mg prednisolone); and dose corticosteroids \>10 mg prednisone equivalent/day, biologics, or immunosuppressive agents following transplantation).