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Endotypic Stability in CRS
Sponsor: Thomas Jefferson University
Summary
A Case control study with 150 cases and 50 controls will be conducted. Immunologic (cytokines measurements in nasal secretions and sinonasal tissues), histopathologic (tissue eosinophilia) and clinical parameters (Lund-Mackay and Lund-Kennedy score, lung function tests), surveys (SNOT- 22, SF-36 quality of life survey) will be compared between different groups of patients
Official title: Comparison of Endotypic Stability in Various Populations With Chronic Sinusitis
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2024-01-01
Completion Date
2027-01-31
Last Updated
2026-10-01
Healthy Volunteers
No
Conditions
Interventions
no intervention
no intervention
Locations (1)
Thomas Jefferson University Department of Otolaryngology
Philadelphia, Pennsylvania, United States