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Predicting Cognition After DBS for Parkinson's Disease 2
Sponsor: Charite University, Berlin, Germany
Summary
The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to avoid risk factors by optimizing peri- and intraoperative management personalize therapeutic strategies for optimal long-term benefit. The investigators will test possible predictors (clinical, neuropsychological, neuroimaging, electrophysiological and molecular) for the risk of cognitive dysfunction after deep brain stimulation of the subthalamic nucleus (STN-DBS) in Parkinson's disease (PD) at a single center (Charité - Universitätsmedizin Berlin, Germany). Data collection takes place prior to as well as 3, 12 and 60 months after the STN-DBS operation. Participation is proposed to all PD patients that are planned to undergo STN-DBS after careful examination of eligibility for this treatment according to standard operation procedures.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-10-01
Completion Date
2030-12-01
Last Updated
2025-09-09
Healthy Volunteers
No
Conditions
Interventions
Neuropsychological Testing
Neuropsychological Testing via Cambridge CANTAB Connect
Locations (1)
Charité - Universitätsmedizin Berlin
Berlin, Germany