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RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
Sponsor: Meyer Children's Hospital IRCCS
Summary
Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all uveitis cases. The diagnosis and management of patients with uveitis rely on a multidisciplinary approach involving an ophthalmologist, a rheumatologist, and an infectious disease specialist to establish the correct diagnosis and assess the involvement of other organs. In Italy, there is no national or regional registry for non-infectious chronic uveitis as per the Prime Ministerial Decree (DPCM) of March 3, 2017 (Identification of surveillance systems and registries for mortality, tumors, and other diseases). However, many clinical centers adopt data recording systems to evaluate the quality of care and to study diseases and outcomes. The Universitary Hospital Meyer Institute Research Hospital (IRCCS) is a national referral center for managing these pediatric cases of non-infectious chronic uveitis, estimated to constitute 95% of all pediatric uveitis cases
Official title: Retrospective and Prospective Observational Study on Non-infectious Chronic Uveitis in Pediatric Age
Key Details
Gender
All
Age Range
1 Year - 16 Years
Study Type
OBSERVATIONAL
Enrollment
290
Start Date
2022-02-10
Completion Date
2032-05-02
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Locations (19)
Children's Mercy Kansas City Division of Rheumatology, Division of Rheumatology
Kansas City, Kansas, United States
The Children's Hospital Corporation d/b/a Boston Children's Hospital
Boston, Massachusetts, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
University fo Gent
Ghent, Belgium
ATTIKON General Hospital
Athens, Greece
Meyer Children's Hospital IRCCS
Florence, Firenze, Italy
Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari
Bari, Italy
Ospedale Spedali Civili di Brescia
Brescia, Italy
Department of Medical of Health Sciences, Magna Grecia University
Catanzaro, Italy
Dipartimento di Immunologia e Reumatologia Pediatrica, Ospedale Vito Fazzi
Lecce, Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico SC Pediatria e Immunoreumatologia PI
Milan, Italy
Unità di Reumatologia ed Immunologia Pediatrica dell'Ospedale Fatebenefratelli Sacco di Milano
Milan, Italy
- UOSD Reumatologia Pediatrica Dipartimento di Salute della Donna e del Bambino Azienda Ospedale Università di Padova
Padova, Italy
Clinica Pediatrica, IRCCS Policlinico San Matteo
Pavia, Italy
IRCCS Ospedale Pediatrico Bambino Gesù Dipartimento Reumatologia
Roma, Italy
Santa Maria Goretti Hospital
Roma, Italy
Unità di Immunologia e Reumatologia, Ospedale Pediatrico Regina Margherita, AOU Città della Salute e della scienza di Torino
Torino, Italy
IRCCS materno infantile Burlo Garofolo
Trieste, Italy
Department of Pediatric Rheumatology, Kocaeli University,
Kocaeli, Turkey (Türkiye)