Clinical Research Directory

Inclusion Criteria: * Healthy adults with a Body mass index (BMI) of 16.00 to 29.99 kg/m2 * Self-reported constipation according to the Rome IV criteria Exclusion Criteria: * Pregnancy * Crohn's disease or any other inflammatory bowel disease * Pelvic floor dyssynergia * Have congenital diseases such as liver disease, diabetes, and thyroid dysfunction. hypercalcemia neurological disease * Drink alcohol or smoke regularly. * During the past 1 month or while in the project, have received antibiotics, steroids, NSAIDs, blood pressure-lowering drugs, antidepressants, anticonvulsants, or Parkinson's disease medications * History of food allergy to Haruna's ingredients * There has been a change in body weight (increase or decrease of 5 kilograms over a period of 6 months). * During the past 2 weeks or while in the project, have received probiotics or other prebiotics