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RECRUITING
NCT06275022
NA

A Prospective Study on the Treatment of cLM Based on ICG Imaging

Sponsor: Nanjing Children's Hospital

View on ClinicalTrials.gov

Summary

The goal of this prospective randomized controlled study is to explore the role of indocyanine green-fluorescence imaging in management of cystic lymphatic malformation.. To clarify the application value of indocyanine green-fluorescence imaging in both diagnosis and treatment of cystic lymphatic malformation (cLM) in children, is helpful for exploring pathogenesis of cLM, and providing a clearer scientific basis for subsequent surgical intervention. It also provides alternative for the future diagnosis and treatment of cLM. Participants will receive indocyanine green-fluorescence imaging before operation, while the patients in control group will receive traditional operation. Researchers will compare difference in curative effect between two groups.

Official title: A Prospective Randomized Controlled Study on the Treatment of Cystic Lymphatic Malformation Based on Indocyanine Green-fluorescence Imaging

Key Details

Gender

All

Age Range

30 Days - 16 Years

Study Type

INTERVENTIONAL

Enrollment

110

Start Date

2023-01-01

Completion Date

2026-03-30

Last Updated

2026-02-18

Healthy Volunteers

No

Interventions

PROCEDURE

Inflow occlusion with perforation of septation and sclerotherapy

Inflow occlusion assisted by indocyanine green-fluorescence imaging combined with perforation of septation and sclerotherapy

PROCEDURE

Perforation of septation and sclerotherapy

Perforation of septation and sclerotherapy

PROCEDURE

Indocyanine green-guided partial resection and sclerotherapy

Indocyanine green-fluorescence imaging-guided partial resection and sclerotherapy

PROCEDURE

Partial resection and sclerotherapy

Partial resection and sclerotherapy

Locations (1)

Children's hospital of Nanjing medical university

Nanjing, Jiangsu, China