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Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSI
Sponsor: Tata Memorial Centre
Summary
The goal of this clinical trial is to evaluate the role of memantine in preservation of memory and neurocognition in patients undergoing craniospinal irradiation. Participants will be randomised into two arms and the interventional arm will receive memantine along with the standard treatment. Researchers will compare the neurocognitive tests of participants in both the arms to see if memantine leads to significant preservation of memory and cognition post radiation therapy.
Official title: Memantine to Preserve Memory and Neurocognition Following Craniospinal Irradiation- A Randomised Controlled Trial (MEMENTO)
Key Details
Gender
All
Age Range
5 Years - 39 Years
Study Type
INTERVENTIONAL
Enrollment
101
Start Date
2024-02-22
Completion Date
2031-01
Last Updated
2025-04-09
Healthy Volunteers
No
Conditions
Interventions
Memantine Oral Tablet
Drug to preserve memory and neurocognitive dysfunction induced by radiation therapy
Locations (1)
Tata Memorial Hospital
Mumbai, Maharashtra, India