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HONEY for the Treatment of POst-Tonsillectomy Pain
Sponsor: East and North Hertfordshire NHS Trust
Summary
Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative outcomes. Main aim is to investigate a potential improvement in post-tonsillectomy pain control, with a low cost and freely available alternative to conventional analgesics. Recent systematic review and multidisciplinary consensus suggest a potential role for the inclusion of honey for this purpose. Clinical efficacy over placebo remains to be conclusively demonstrated in robust clinical trials.
Official title: HONEY for the Treatment of POst-Tonsillectomy Pain - a Double-blind, Randomised, Placebo Controlled, Single Site Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-09-04
Completion Date
2025-09-04
Last Updated
2025-04-29
Healthy Volunteers
Yes
Conditions
Interventions
Manuka honey MGO 1000
Natural Manuka honey, produced in New Zealand. With MGO content ≥ 1000.
Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring
Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring, 15ml, three times a day, for 14 days. To be kept on the tongue for at least 10 seconds prior to swallowing.
Locations (1)
Lister Hospital
Stevenage, United Kingdom