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Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
Sponsor: The Hong Kong Polytechnic University
Summary
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram. The main questions it aims to answer are: * the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control in children with different myopia progression rates * the contribution of L/M cones in juvenile myopia progression and changes of retinal activities under atropine and DIMS treatment. Participants will have baseline and follow-up eye examinations and given either pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens for myopia control. Researchers will compare the changes of refractive errors and axial length after different types of interventions and investigate the relations between the parameters of mfERG responses and the thicknesses of retinal layers and choroid.
Official title: Pharmacological (0.05% Atropine) and Non-pharmacological (Defocused Incorporated Multiple Segments Lens) Treatment Effects on the Children With Different Predicted Myopia Progression Rate Measured by Modified Multifocal Electroretinogram
Key Details
Gender
All
Age Range
7 Years - 9 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-01-01
Completion Date
2026-12
Last Updated
2025-09-17
Healthy Volunteers
Yes
Conditions
Interventions
Atropine 0.05%
Topical application
DIMS lens
Spectacle wear
Locations (1)
School of Optometry, Hong Kong Polytechnic University
Hong Kong, Hong Kong