Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06282848
NA

Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate

Sponsor: The Hong Kong Polytechnic University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram. The main questions it aims to answer are: * the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control in children with different myopia progression rates * the contribution of L/M cones in juvenile myopia progression and changes of retinal activities under atropine and DIMS treatment. Participants will have baseline and follow-up eye examinations and given either pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens for myopia control. Researchers will compare the changes of refractive errors and axial length after different types of interventions and investigate the relations between the parameters of mfERG responses and the thicknesses of retinal layers and choroid.

Official title: Pharmacological (0.05% Atropine) and Non-pharmacological (Defocused Incorporated Multiple Segments Lens) Treatment Effects on the Children With Different Predicted Myopia Progression Rate Measured by Modified Multifocal Electroretinogram

Key Details

Gender

All

Age Range

7 Years - 9 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-01-01

Completion Date

2026-12

Last Updated

2025-09-17

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Atropine 0.05%

Topical application

DEVICE

DIMS lens

Spectacle wear

Locations (1)

School of Optometry, Hong Kong Polytechnic University

Hong Kong, Hong Kong