Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.
Sponsor: National Cheng-Kung University Hospital
Summary
This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
105
Start Date
2021-01-01
Completion Date
2025-05-31
Last Updated
2025-05-29
Healthy Volunteers
No
Conditions
Interventions
Povidone-iodine solution; chlorhexidine gluconate
Before wound closure, each group will undergo different irrigation solutions for soaking the wound for three minutes followed by rinsing with copious saline.
Locations (1)
National Cheng Kung University Hospital
Tainan, Taiwan, Taiwan