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RECRUITING
NCT06286163

Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients

Sponsor: Imperial College London

View on ClinicalTrials.gov

Summary

This study is being done in order to understand what causes people to have a chronic cough, which is defined as a cough lasting for more than 8 weeks. The research team wish to find out whether there is any inflammation in the lungs of patients with chronic cough. The research team will also determine whether a suspected chemical produced in the body, called adenosine triphosphate (ATP) can be responsible for causing the chronic cough. In order to be able to find out what is abnormal in those who have a chronic cough, The research team will need to compare their results with those that do not have a chronic cough. In this study, the research team will examine 10 participants who suffer from chronic cough and 8 individuals who do not have a chronic cough and are healthy.

Official title: Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients: an Exploratory Study

Key Details

Gender

All

Age Range

30 Years - 70 Years

Study Type

OBSERVATIONAL

Enrollment

18

Start Date

2023-10-01

Completion Date

2025-12-31

Last Updated

2025-02-07

Healthy Volunteers

Yes

Conditions

Locations (2)

Royal Brompton & Harefield NHS Trust,

London, United Kingdom

Royal Brompton Hospital

London, United Kingdom