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Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients
Sponsor: Imperial College London
Summary
This study is being done in order to understand what causes people to have a chronic cough, which is defined as a cough lasting for more than 8 weeks. The research team wish to find out whether there is any inflammation in the lungs of patients with chronic cough. The research team will also determine whether a suspected chemical produced in the body, called adenosine triphosphate (ATP) can be responsible for causing the chronic cough. In order to be able to find out what is abnormal in those who have a chronic cough, The research team will need to compare their results with those that do not have a chronic cough. In this study, the research team will examine 10 participants who suffer from chronic cough and 8 individuals who do not have a chronic cough and are healthy.
Official title: Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients: an Exploratory Study
Key Details
Gender
All
Age Range
30 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
18
Start Date
2023-10-01
Completion Date
2025-12-31
Last Updated
2025-02-07
Healthy Volunteers
Yes
Conditions
Locations (2)
Royal Brompton & Harefield NHS Trust,
London, United Kingdom
Royal Brompton Hospital
London, United Kingdom