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Regional Anesthesia EMG Study
Sponsor: Nationwide Children's Hospital
Summary
This study aims to investigate how non-invasive, non-significant risk EMG monitoring can be used intraoperatively to objectively characterize neuraxial anesthesia (i.e. spinal and caudal blockade) in pediatric patients undergoing surgery. The investigators will also attempt to measure the effect of adjunctive intrathecal clonidine on spinal and caudal blockade using EMG. This study also aims to quantify the impact of sevoflurane on basal muscle tone based on EMG changes. This study aims to generate pilot data on this subject to help design future studies.
Official title: Assessment of Regional Anesthetic Blockade Using Non-Invasive Surface Electromyogram (EMG)
Key Details
Gender
All
Age Range
0 Years - 5 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2023-08-09
Completion Date
2025-02-28
Last Updated
2026-08-06
Healthy Volunteers
No
Conditions
Interventions
BlockSynop surface electromyography device
The EMG monitor uses non-invasive surface electrodes that measures electrical activity in response to muscle stimulation. After all electrodes have been placed on the patient, the electrodes will be connected to a prototype non-significant risk device (NSR) BlockSynop surface electromyography device and monitoring of sEMG signal will begin. The device is a non-invasive and non-significant risk device.
Clonidine
Clonidine is an alpha-2-agonist which is commonly used as an adjunct in spinal anesthesia and caudal anesthesia to improve both the quality and duration of blockade.
Sevoflurane
5.3. Sevoflurane is FDA approved for the induction and maintenance of general anesthesia in adults and pediatric patients.
Locations (1)
Nationwide Children's Hospital
Columbus, Ohio, United States