Clinical Research Directory
Browse clinical research sites, groups, and studies.
Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery
Sponsor: Imperial College London
Summary
Oesophagogastric cancer (cancer of the gullet and stomach) is the fifth most common cancer in England and Wales with 16,000 new cases diagnosed every year. Survival rates are poor with only 15% surviving beyond 5 years. There is also increasing research to understand the cancer biology and factors allowing cancers to progress. It is likely there is a relationship between the cancer-specific microbiome, cells related to inflammation, which promotes cancer progression. The BIORESOURCE 1 study has established a comprehensive resource of matched samples from patients with oesophageal and gastric cancer. This longitudinal study aims to obtain further matched biosamples in the follow-up period after cancer surgery to find biomarkers that may predict treatment response, recurrence and/or long term prognosis.
Official title: The LABS Study: Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery (BIORESOURCE 2: Longitudinal)
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-02
Completion Date
2029-06
Last Updated
2025-02-19
Healthy Volunteers
No
Interventions
Biosample collection
Collection of saliva, urine, blood, breath and quality of life questionnaires.
Locations (1)
Imperial College Healthcare NHS Trust
London, United Kingdom