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Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial
Sponsor: King Chulalongkorn Memorial Hospital
Summary
The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are: * The efficacy in reducing blood transfusion for topical tranexamic acid administration * The safety of tranexemic acid, topically used As having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration. Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion.
Official title: Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Bipolar Hemiarthroplasty
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2024-07-03
Completion Date
2027-06-30
Last Updated
2026-08-05
Healthy Volunteers
Yes
Conditions
Interventions
Retrograde Intraarticular Injection via Drain Tube
Tranexamic acid will be injected via drain tube after wound closure
Topical Soaking of Tranexamic Acid
Tranexamic acid will be topically administered by soaking method
Placebo Comparator: Standard procedure (placebo)
Standard wound management
Locations (2)
Faculty of Medicine, King Chulalongkorn Memorial Hospital
Bangkok, Bangkok, Thailand
Faculty of Medicine
Bangkok, Bangkok, Thailand