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Predictors of Post-COVID-19 Clinical and Cognitive Consequences
Sponsor: VA Office of Research and Development
Summary
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.
Official title: Predictors of Post-COVID Clinical and Cognitive Consequences
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2023-01-19
Completion Date
2026-12-31
Last Updated
2026-01-23
Healthy Volunteers
Yes
Locations (1)
John D. Dingell VA Medical Center, Detroit, MI
Detroit, Michigan, United States