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Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer
Sponsor: The University of Hong Kong
Summary
About 80% of advanced ovarian cancer patients recurred in 2-3 years. Secondary cytoreduction benefits selected patients who have high chance of complete resection. Whether secondary interval surgery can be used at recurrence is not known.
Official title: Secondary Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer Patients - a Pilot Study
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
18
Start Date
2023-11-01
Completion Date
2026-12-31
Last Updated
2025-06-11
Healthy Volunteers
No
Conditions
Interventions
Carboplatin or cisplatin
Carboplatin of cisplatin for 3-6 cycles
Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar
Paclitaxel, gemcitabine or liposomal doxorubicin, for 3-6 cycles
Bevacizumab or biosimilar
Optional
Cytoreductive surgery
Cytoreductive surgery after chemotherapy
Locations (1)
The University of Hong Kong
Hong Kong, Hong Kong