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RECRUITING
NCT06292286
NA

Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer

Sponsor: The University of Hong Kong

View on ClinicalTrials.gov

Summary

About 80% of advanced ovarian cancer patients recurred in 2-3 years. Secondary cytoreduction benefits selected patients who have high chance of complete resection. Whether secondary interval surgery can be used at recurrence is not known.

Official title: Secondary Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer Patients - a Pilot Study

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2023-11-01

Completion Date

2026-12-31

Last Updated

2025-06-11

Healthy Volunteers

No

Interventions

PROCEDURE

Carboplatin or cisplatin

Carboplatin of cisplatin for 3-6 cycles

DRUG

Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar

Paclitaxel, gemcitabine or liposomal doxorubicin, for 3-6 cycles

DRUG

Bevacizumab or biosimilar

Optional

PROCEDURE

Cytoreductive surgery

Cytoreductive surgery after chemotherapy

Locations (1)

The University of Hong Kong

Hong Kong, Hong Kong