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4AP for Carpal Tunnel Syndrome (CTS)
Sponsor: John Elfar
Summary
The investigators have found recent promising data supporting the use of a currently FDA approved drug, 4-aminopyridine, in the treatment of nerve injury including compression neuropathy. The purpose of this research is determine whether 4-aminopyridine can treat carpal tunnel syndrome or delay the need for formal surgical release in patients with known carpal tunnel syndrome who would otherwise undergo surgery.
Official title: 4-Aminopyridine to Delay Carpal Tunnel Release or Resolve Carpal Tunnel Syndrome
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-11
Completion Date
2028-07
Last Updated
2026-01-26
Healthy Volunteers
No
Interventions
4-Aminopyridine
Subjects will receive either the active study drug (4-aminopyridine) or placebo to determine the effects of 4AP on carpal tunnel syndrome
Placebo
Subjects will receive either the active study drug (4-aminopyridine) or placebo to determine the effects of 4AP on carpal tunnel syndrome