Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis
Sponsor: Pfizer
Summary
The purpose of this real world non-interventional study is to learn about the effects of etrasimod as treatment for patients with moderate to severe ulcerative colitis. Patients will be treated according to standard of care and will only be included in the study if etrasimod is the best treatment choice according to the treating physician. Additionally, patients have to be between 18 and 65 years of age and should not have taken etrasimod in the past. All patients will be prescribed etrasimod according to standard of care. Assessments will be conducted according to standard of care with the exception of health questionnaires which will be completed by the patients online on their own device. The study duration is 52 weeks with 28 days of safety follow-up. Patients will visit their treating physician as they would if they were not enrolled in the study. During the study duration, patients will be asked to complete health questionnaires on a regular basis either on their mobile phone, tablet or computer. The effects of etrasimod will be analyzed for each patient comparing to their disease activity prior to the start of etrasimod.
Official title: Effectiveness of Etrasimod on Disease Activity and Patient-reported Outcomes in Ulcerative Colitis - EFFECT-UC
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
OBSERVATIONAL
Enrollment
360
Start Date
2024-05-08
Completion Date
2026-06-30
Last Updated
2026-03-30
Healthy Volunteers
No
Conditions
Interventions
Etrasimod
As provided in real world practice
Locations (34)
Vancouver Coastal Health
Vancouver, British Columbia, Canada
Providence Health Care (PHC)
Vancouver, British Columbia, Canada
London Health Sciences Centre
London, Ontario, Canada
CHUM
Montreal, Quebec, Canada
Montreal General Hospital
Montreal, Quebec, Canada
Gastroenterologie OpernstraBe
Kassel, Hesse, Germany
MVZ Gastroenterologie Aachen
Aachen, Germany
Praxis Heil und Müller
Andernach, Germany
MVZ für Gastroenterologie am Bayerischen Platz
Berlin, Germany
Evangelisches Krankenhaus Kalk
Cologne, Germany
MVZ Dachau
Dachau, Germany
Interdisziplinares Crohn Colitis Centrum
Frankfurt am Main, Germany
Facharztpraxis für Gastroenterologie
Grevenbroich, Germany
Studiengesellschaft BSF UG.
Halle, Germany
Praxis für Gasteroenterologie
Heidelberg, Germany
Praxis für Gasteroenterologie Lübeck
Lübeck, Germany
Klinikum Lüneburg
Lüneburg, Germany
Internistische Praxengemeinschaft Oldenburg
Oldenburg, Germany
Magen-Darm-Zentrum Remscheid
Remscheid, Germany
CED am Rhein
Wesseling, Germany
NHS Greater Glasgow and Clyde
Glasgow, Lanarkshire, United Kingdom
Nottingham University Hospitals NHS Trust, Queens Medical Centre
Nottingham, Nottinghamshire, United Kingdom
Oxford University Hospitals NHS Foundation Trust
Oxford, Oxfordshire, United Kingdom
Western General Hospital
Edinburgh, Scotland, United Kingdom
Northern Care Alliance NHS Foundation Trust, Greater Manchester
Crumpsall, United Kingdom
Tunbridge Wells Hospital
Kent, United Kingdom
Barts Health NHS Trust, The Royal London Hospital
London, United Kingdom
St. Mark's Hospital
London, United Kingdom
University College London Hospital
London, United Kingdom
St Thomas' Hospital - Guy's & St Thomas' NHS Foundation Trust
London, United Kingdom
Kings College Hospital
London, United Kingdom
St George's Hospital - St George's Healthcare Nhs Trust
London, United Kingdom
Imperial College Healthcare NHS
London, United Kingdom
Southampton University Hospitals NHS Trust
Southampton, United Kingdom