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RECRUITING
NCT06295822
NA

The Effectiveness of Chinese Medicine Nuan-gong-ye on Primary Dysmenorrhea

Sponsor: China Medical University Hospital

View on ClinicalTrials.gov

Summary

Primary dysmenorrhea is a common under-diagnosed complaint, with a prevalence of about 45-95% in women of childbearing age and about 10-25% in severe cases. Menstrual pain can be classified as primary or secondary. Primary menstrual pain is a crampy pain in the lower abdomen without any pelvic pathology, which usually occurs 6 to 12 months after the first menstruation. Primary menstrual pain is usually most severe on the first day of the menstrual cycle and lasts for 8 to 72 hours. The cause is still unknown, but studies suggest that it may be related to increased prostaglandins, which cause painful contractions of the uterus. The pain is often accompanied by other menstrual discomfort symptoms, including headache, breast tenderness, drowsiness, nausea, vomiting, constipation or diarrhea, and psychological anxiety, depression or irritability. In the case of secondary menstrual pain, there are clear pelvic pathologies, such as endometriosis, uterine fibroids, and pelvic inflammatory disease.

Key Details

Gender

FEMALE

Age Range

20 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

82

Start Date

2024-03-04

Completion Date

2026-02-28

Last Updated

2024-04-10

Healthy Volunteers

Yes

Interventions

DRUG

Nuan-gong-ye

In this study, the ingredients of nuan-gong-ye are myrrh, dragon's blood, yanhu tuber, white mustard seed, asarum root, argy wormwood leaf, holly oil, clove oil, cinnamon bark oil, glycerin, PEG400.

OTHER

Placebo

The placebo was 1/20 concentration of nuan-gong-ye plus glycerin and PEG400.

Locations (1)

China Medical University Hospital

Taichung, Taiwan