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RECRUITING
NCT06296732

Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification

Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

View on ClinicalTrials.gov

Summary

Surgery plays significant role in treatment of neurogenic tumors, both for benign ganglioneuroma and for high risk neuroblastoma. The world literature has accumulated large experience in laparoscopic surgery for abdominal neuroblastoma. The presence of IDRF (image-defined risk factors) and tumor size (\>4-7 cm) are considered as common contraindications for minimally invasive surgery in neuroblastoma. However, the recent studies have shown that presence of IDRF is not an absolute contraindication for laparoscopic surgery. This open-label, nonrandomized, observational, phase III evaluates role and weight of different surgical risk factors (including IDRF, tumor size, tumor localization, tumor volume/patient height ratio, previous open surgical procedures, previous chemotherapy etc.) in the laparoscopic neuroblastoma resections. The aim of this study is to create novel risk factors scoring system for laparoscopic surgery in abdominal neuroblastoma.

Key Details

Gender

All

Age Range

1 Day - 18 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-10-19

Completion Date

2031-11-01

Last Updated

2024-05-20

Healthy Volunteers

Not specified

Interventions

PROCEDURE

Duration of surgery intervention

Intraoperative- duration from the beginning of the skin incision to skin suture (min)

Locations (1)

Research Institute of Pediatric Hematology, Oncology and Immunology

Moscow, Russia