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Characterization of Exosomes Platelets-released
Sponsor: Centro Cardiologico Monzino
Summary
Extracellular vesicles (EVs) play a key role in cell-to-cell communication. They are small vesicles that contain rich molecular cargo. Recently, they have been proposed as biomarkers for clinical diagnostics. EVs include three classes: small EVs (exosomes), large EVs (microparticles), and apoptotic bodies. Platelet-derived EVs (PEVs) are the most abundant class in human blood and can actively participate in numerous physiological and pathological processes. The information about the role of platelet exosomes in cardiovascular disease and the effect of antiplatelet agents on their release and content is very limited.
Key Details
Gender
All
Age Range
20 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
175
Start Date
2021-07-08
Completion Date
2027-07-07
Last Updated
2024-03-12
Healthy Volunteers
Yes
Conditions
Locations (1)
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy