Clinical Research Directory
Browse clinical research sites, groups, and studies.
Efficacy of Combination of Hdroxyurea and Thalidomide Over Hydroxyurea or Thalidomide in the Treatment of Transfusion Dependent Thalassemia in Children
Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Summary
The goal of this clinical trial is to find out the efficacy of combined Hydroxyurea and thalidomide transfusion dependent thalassemia patients. The main objectives are to compare the level of Hb, Transfusion interval, serum ferritin level before \& after treatment between single and combination of thalidomide and HU. Researcher will compare the effectiveness of combined hydroxyurea and thalidomide and hydroxyurea and thalidomide alone. Participants will be divided in three groups: Group I: will take combination of HU and Thalidomide. Group II: Will take HU alone and Group III: Will take Thalidomide alone and outcome will be recorded.
Official title: Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial
Key Details
Gender
All
Age Range
3 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2023-11-01
Completion Date
2026-01-30
Last Updated
2026-06-17
Healthy Volunteers
No
Conditions
Interventions
Thalidomide
Patients will get only Thalidomide
Hydroxy Urea
Patients will get only Hydroxyurea
Combinations
Combination Of Thalidomide \& Hydroxyurea
Locations (1)
Bangabandhu Sheikh Mujib Medical University
Dhaka, Bangladesh