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Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells
Sponsor: abdulmajeed hammadi
Summary
investigator is doing single armed clinical interventional study to treat premature ovarian insufficiency with autologous bone marrow derived mononuclear cells to be given systematically and locally to the ovaries under ultrasound guidance with experienced gynecologist and to look for the results including: laboratory evidence through hormonal study ultrasound proof of ovarian follicle development. premature ovarian insufficiency is characterized by early loss of ovarian function (less than 40 years of age) manifested by menstrual irregularity or amenorrhea with elevated levels of gonadotropin hormones and low estrogen and anti-Mullerian hormone. Autologous use of stem cells from bone marrow are alternative safe minimal manipulative products that can provide a solution to this clinical problem without the need for oocyte donation program.
Official title: Treatment of Premature Ovarian Insufficiency Using Autologous Bone Marrow Concentrates Through Transvaginal Approach Under Ultrasound Guidance
Key Details
Gender
FEMALE
Age Range
30 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2024-03-01
Completion Date
2026-03-10
Last Updated
2025-08-05
Healthy Volunteers
Yes
Conditions
Interventions
autologous bone marrow cells injection
under general anesthesia bone marrow aspiration done followed by cell concentration and transvaginal ovarian injection
Locations (1)
Ministry of Health
Baghdad, Iraq