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RECRUITING
NCT06302543
NA

Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells

Sponsor: abdulmajeed hammadi

View on ClinicalTrials.gov

Summary

investigator is doing single armed clinical interventional study to treat premature ovarian insufficiency with autologous bone marrow derived mononuclear cells to be given systematically and locally to the ovaries under ultrasound guidance with experienced gynecologist and to look for the results including: laboratory evidence through hormonal study ultrasound proof of ovarian follicle development. premature ovarian insufficiency is characterized by early loss of ovarian function (less than 40 years of age) manifested by menstrual irregularity or amenorrhea with elevated levels of gonadotropin hormones and low estrogen and anti-Mullerian hormone. Autologous use of stem cells from bone marrow are alternative safe minimal manipulative products that can provide a solution to this clinical problem without the need for oocyte donation program.

Official title: Treatment of Premature Ovarian Insufficiency Using Autologous Bone Marrow Concentrates Through Transvaginal Approach Under Ultrasound Guidance

Key Details

Gender

FEMALE

Age Range

30 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2024-03-01

Completion Date

2026-03-10

Last Updated

2025-08-05

Healthy Volunteers

Yes

Interventions

PROCEDURE

autologous bone marrow cells injection

under general anesthesia bone marrow aspiration done followed by cell concentration and transvaginal ovarian injection

Locations (1)

Ministry of Health

Baghdad, Iraq